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1

Exploring Side-Chain Diversity by Submonomer Solid-Phase Aza-Peptide Synthesis

Sabatino, David, Proulx, Caroline, Klocek, Sophie, Bourguet, Carine B., Boeglin, Damien, Ong, Huy, Lubell, William D.

Journal:

Organic Letters

Year:

2009

Language:

english

File:

PDF, 514 KB

english, 2009

2

Azapeptide Analogues of the Growth Hormone Releasing Peptide 6 as Cluster of Differentiation 36 Receptor Ligands with Reduced Affinity for the Growth Hormone Secretagogue Receptor 1a

Proulx, Caroline, Picard, Émilie, Boeglin, Damien, Pohankova, Petra, Chemtob, Sylvain, Ong, Huy, Lubell, William D.

Journal:

Journal of Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 3.05 MB

english, 2012

3

Aza-Amino Acid Scan for Rapid Identification of Secondary Structure Based on the Application of N -Boc-Aza 1 -Dipeptides in Peptide Synthesis

Melendez, Rosa E., Lubell, William D.

Journal:

Journal of the American Chemical Society

Year:

2004

Language:

english

File:

PDF, 122 KB

english, 2004

4

Azapeptides and their therapeutic potential

Proulx, Caroline, Sabatino, David, Hopewell, Robert, Spiegel, Jochen, García Ramos, Yésica, Lubell, William D.

Journal:

Future Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 1.87 MB

english, 2011

5

HYDRA: A novel hydroxy and amine functionalised resin synthesised by reductive amination of PEG aldehyde and a polyamine

Groth, Thomas, Grøtli, Morten, Lubell, William D., Miranda, Les P., Meldal, Morten

Journal:

Journal of the Chemical Society Perkin Transactions 1

Year:

2000

Language:

english

File:

PDF, 897 KB

english, 2000

6

A Novel Linking-Protecting Group Strategy for Solid-Phase Organic Chemistry with Configurationally Stable α-[ N -(Phenylfluorenyl)]amino Carbonyl Compounds: Synthesis of Enantiopure Norephedrines on Solid Support

Gosselin, Francis, Van Betsbrugge, Jo, Hatam, Mostafa, Lubell, William D.

Journal:

Journal of Organic Chemistry

Year:

1999

Language:

english

File:

PDF, 117 KB

english, 1999

7

Aza-Amino Acid Scanning of Secondary Structure Suited for Solid-Phase Peptide Synthesis with Fmoc Chemistry and Aza-Amino Acids with Heteroatomic Side Chains

Boeglin, Damien, Lubell, William D.

Journal:

Journal of Combinatorial Chemistry

Year:

2005

Language:

english

File:

PDF, 571 KB

english, 2005

8

[Advances in Experimental Medicine and Biology] Peptides for Youth Volume 611 || Stimuli-responsive Peptide Self-assembly into Well-organized Nanofibers

Valle, Susan Del, Escher, Emanuel, Lubell, William D.

Year:

2009

Language:

english

File:

PDF, 1.96 MB

english, 2009

9

Applications of γ,δ-Unsaturated Ketones Synthesized by Copper-Catalyzed Cascade Addition of Vinyl Grignard Reagents to Esters

Douchez, Antoine, Geranurimi, Azade, Lubell, William D.

Journal:

Accounts of Chemical Research

Year:

2018

Language:

english

File:

PDF, 3.33 MB

english, 2018

10

Solid-Phase Azopeptide Diels-Alder Chemistry for Aza-Pipecolyl Residue Synthesis to Study Peptide Conformation

Chingle, Ramesh, Mulumba, Mukandila, Chung, Nga N., Nguyen, Thi Mai-Dung, Ong, Huy, Ballet, Steven, Schiller, Peter W., Lubell, William D.

Journal:

Journal of Organic Chemistry

Year:

2019

File:

PDF, 1000 KB

2019

11

An examination of the steric effects of 5-tert-butylproline on the conformation of polyproline and the cooperative nature of type II to type I helical interconversion

Eric Beausoleil, William D. Lubell

Journal:

Year:

2000

Language:

english

File:

PDF, 114 KB

english, 2000

12

Design, synthesis, and conformational analysis of azacycloalkane amino acids as conformationally constrained probes for mimicry of peptide secondary structures

Liliane Halab, Francis Gosselin, William D. Lubell

Journal:

Year:

2000

Language:

english

File:

PDF, 435 KB

english, 2000

13

Design, synthesis, and application of azabicyclo[X.Y.0]alkanone amino acids as constrained dipeptide surrogates and peptide mimics

Jérôme Cluzeau, William D. Lubell

Journal:

Year:

2005

Language:

english

File:

PDF, 3.71 MB

english, 2005

14

Homoserine-derived cyclic sulfamidate as chiral educt for the diversity-oriented synthesis of lactam-bridged dipeptides

Fabrice Galaud, William D. Lubell

Journal:

Year:

2005

Language:

english

File:

PDF, 190 KB

english, 2005

15

Synthesis of a new π-deficient phenylalanine derivative from a common 1,4-diketone intermediate and study of the influence of aromatic density on prolyl amide isomer population

Aurélie Dörr, William D. Lubell

Journal:

Year:

2007

Language:

english

File:

PDF, 320 KB

english, 2007

16

Benzophenone semicarbazone protection strategy for synthesis of aza-glycine containing aza-peptides

Carine B. Bourguet, David Sabatino, William D. Lubell

Journal:

Year:

2008

Language:

english

File:

PDF, 480 KB

english, 2008

17

Insertion of multiple α-amino γ-lactam (Agl) residues into a peptide sequence by solid-phase synthesis on synphase lanterns

Luisa Ronga, Andrew G. Jamieson, Kim Beauregard, Christiane Quiniou, Sylvain Chemtob, William D. Lubell

Journal:

Year:

2010

Language:

english

File:

PDF, 672 KB

english, 2010

18

Thoughts on Meldal and Hirschmann

William D. Lubell

Journal:

Year:

2010

Language:

english

File:

PDF, 216 KB

english, 2010

19

Conjugated 4-Methoxybipyrrole Thiophene Azomethines: Synthesis, Opto-Electronic Properties, and Crystallographic Characterization

Tshitundu Tshibaka, Sophie Bishop, Ivan Ulliel Roche, Stéphane Dufresne, William D. Lubell, William G. Skene

Journal:

Chemistry - A European Journal

Year:

2011

Language:

english

File:

PDF, 1.83 MB

english, 2011

20

Inside Cover: Conjugated 4-Methoxybipyrrole Thiophene Azomethines: Synthesis, Opto-Electronic Properties, and Crystallographic Characterization (Chem. Eur. J. 39/2011)

Tshitundu Tshibaka, Sophie Bishop, Ivan Ulliel Roche, Stéphane Dufresne, William D. Lubell, William G. Skene

Journal:

Chemistry - A European Journal

Year:

2011

File:

PDF, 903 KB

2011

21

ChemInform Abstract: An Olefination Entry for the Synthesis of Enantiopure α,ω-Diaminodicarboxylates and Azabicyclo[X.Y.0]alkane Amino Acids.

Francis Gosselin, William D. Lubell

Journal:

Year:

1999

File:

PDF, 36 KB

1999

22

ChemInform Abstract: Alkyl Substituent Effects on Pipecolyl Amide Isomer Equilibrium: Efficient Methodology for Synthesizing Enantiopure 6-Alkylpipecolic Acids and Conformational Analysis of Their N-Acetyl N′-Methylamides.

Martin E. Swarbrick, Francis Gosselin, William D. Lubell

Journal:

Year:

1999

Language:

english

File:

PDF, 37 KB

english, 1999

23

ChemInform Abstract: Synthesis and Pharmacology of New Enantiopure Δ3-4-Arylkainoids.

Dany Rondeau, Patrice Gill, Monique Chan, Kenneth Curry, William D. Lubell

Journal:

Year:

2000

File:

PDF, 31 KB

2000

24

ChemInform Abstract: Rigid Dipeptide Surrogates: Syntheses of Enantiopure Quinolizidinone and Pyrroloazepinone Amino Acids from a Common Diaminodicarboxylate Precursor.

Francis Gosselin, William D. Lubell

Journal:

Year:

2000

File:

PDF, 36 KB

2000

25

ChemInform Abstract: Efficient Synthesis of 1-Benzyloxyphenyl-3-phenylacetones.

Els Mannekens, Dirk Tourwe, William D. Lubell

Journal:

Year:

2000

File:

PDF, 26 KB

2000

26

ChemInform Abstract: Racemization in the Use of N-(9-(9-Phenylfluorenyl))serine-derived Cyclic Sulfamidates in the Synthesis of δ-Keto α-Amino Carboxylates and Prolines.

Lan Wei, William D. Lubell

Journal:

Year:

2000

File:

PDF, 34 KB

2000

27

ChemInform Abstract: Design, Synthesis, and Conformational Analysis of Azacycloalkane Amino Acids as Conformationally Constrained Probes for Mimicry of Peptide Secondary Structures

Liliane Halab, Francis Gosselin, William D. Lubell

Journal:

Year:

2001

File:

PDF, 25 KB

2001

28

ChemInform Abstract: Scope and Limitations in the Use of N-(PhF)Serine-Derived Cyclic Sulfamidates for Amino Acid Synthesis.

Lan Wei, William D. Lubell

Journal:

Year:

2001

File:

PDF, 35 KB

2001

29

ChemInform Abstract: N-(9-(9-Phenylfluorenyl))homoserine-Derived Cyclic Sulfamidates: Novel Chiral Educts for the Synthesis of Enantiopure γ-Substituted α-Amino Acids.

Mohamed Atfani, Lan Wei, William D. Lubell

Journal:

Year:

2002

File:

PDF, 37 KB

2002

30

An Effective New Synthesis of 4-Aminopyrrole-2-carboxylates.

Felix-Antoine Marcotte, William D. Lubelle

Journal:

Year:

2002

File:

PDF, 34 KB

2002

31

Synthesis and Reactivity of Cyclic Sulfamidites and Sulfamidates.

Rosa E. Melendez, William D. Lubell

Journal:

Year:

2003

File:

PDF, 54 KB

2003

32

Diversity-Oriented Synthesis of Functionalized Pyrrolo[3,2-d]pyrimidines with Variation of the Pyrimidine Ring Nitrogen Substituents.

Felix-Antoine Marcotte, Frederik J. R. Rombouts, William D. Lubell

Journal:

Year:

2004

File:

PDF, 112 KB

2004

33

One-Pot Synthesis of Homoallylic Ketones from the Addition of Vinyl Grignard Reagent to Carboxylic Esters.

Karl A. Hansford, James E. Dettwiler, William D. Lubell

Journal:

Year:

2004

File:

PDF, 124 KB

2004

34

Diversity-Oriented Synthesis of Enantiopure N-Protected β,β-Dialkylserines.

James E. Dettwiler, William D. Lubell

Journal:

Year:

2004

File:

PDF, 208 KB

2004

35

Synthesis of Fused Heteroarylprolines and Pyrrolopyrroles.

Guillaume Jeannotte, William D. Lubell

Journal:

Year:

2004

File:

PDF, 44 KB

2004

36

Selective tert-Butyl Ester Deprotection in the Presence of Acid Labile Protecting Groups with Use of ZnBr2.

Ramesh Kaul, Yann Brouillette, Zohreh Sajjadi, Karl A. Hansford, William D. Lubell

Journal:

Year:

2005

File:

PDF, 38 KB

2005

37

Synthesis and Evaluation of 4-(1-Aminoalkyl)-N-(4-pyridyl)cyclohexanecarboxamides as Rho Kinase Inhibitors and Neurite Outgrowth Promoters.

Karine Gingras, Hovsep Avedissian, Eryk Thouin, Veronique Boulanger, Charles Essagian, Lisa McKerracher, William D. Lubell

Journal:

Year:

2005

Language:

english

File:

PDF, 206 KB

english, 2005

38

Three-Step Solution-Phase Combinatorial Access to 1,2-Disubstituted and 1,2,5-Trisubstituted Pyrroles from Carboxylic Esters.

Karl A. Hansford, Valeria Zanzarova, Aurelie Doerr, William D. Lubell

Journal:

Year:

2005

File:

PDF, 26 KB

2005

39

Design, Synthesis, and Application of Azabicyclo[X.Y.O]alkanone Amino Acids as Constrained Dipeptide Surrogates and Peptide Mimics

Jerome Cluzeau, William D. Lubell

Journal:

Year:

2005

File:

PDF, 8 KB

2005

40

Bis(pyrrol-2-yl)arylenes from the Tandem Bidirectional Addition of Vinyl Grignard Reagent to Aryl Diesters.

Karl A. Hansford, Sergio Andres Perez Guarin, W. G. Skene, William D. Lubell

Journal:

Year:

2006

File:

PDF, 30 KB

2006

41

Asymmetric synthesis of α-amino β-hydroxy phosphonic acids via BINAP-ruthenium catalyzed hydrogenation

Masato Kitamura, Makoto Tokunaga, Trang Pham, William D. Lubell, Ryoji Noyori

Journal:

Tetrahedron Letters

Year:

1995

Language:

english

File:

PDF, 245 KB

english, 1995

42

Fluorometric assay for tissue transglutaminase-mediated transamidation activity

Claudio Gnaccarini, Wajih Ben-Tahar, William D. Lubell, Joelle N. Pelletier, Jeffrey W. Keillor

Journal:

Bioorganic & Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 364 KB

english, 2009

43

Pyrrole protection

Benoit Jolicoeur, Erin E. Chapman, Alison Thompson, William D. Lubell

Journal:

Year:

2006

Language:

english

File:

PDF, 2.51 MB

english, 2006

44

Synthesis and peptide coupling of protected 2-pyrrolylalanine

Aurélie A. Dörr, William D. Lubell

Journal:

Tetrahedron Letters

Year:

2011

Language:

english

File:

PDF, 283 KB

english, 2011

45

Improved synthesis of (2S,5S)-5-tert-butylproline

Liliane Halab, Laurent Bélec, William D Lubell

Journal:

Year:

2001

Language:

english

File:

PDF, 170 KB

english, 2001

46

Synthesis and reactivity of cyclic sulfamidites and sulfamidates

Rosa E. Meléndez, William D. Lubell

Journal:

Year:

2003

Language:

english

File:

PDF, 3.33 MB

english, 2003

47

Design and synthesis of conformationally constrained amino acids as versatile scaffolds and peptide mimetics

Stephen Hanessian, Grant McNaughton-Smith, Henry-Georges Lombart, William D. Lubell

Journal:

Year:

1997

Language:

english

File:

PDF, 2.62 MB

english, 1997

48

Effective synthesis of enantiopure hydroxamates by displacement of resin-bound esters with hydroxylamine

Eryk Thouin, William D Lubell

Journal:

Tetrahedron Letters

Year:

2000

Language:

english

File:

PDF, 184 KB

english, 2000

49

Enantioselective synthesis of β-amino acids based on BINAP—ruthenium(II) catalyzed hydrogenation

William D. Lubell, Masato Kitamura, Ryoji Noyori

Journal:

Tetrahedron: Asymmetry

Year:

1991

Language:

english

File:

PDF, 860 KB

english, 1991

50

Synthesis and pharmacology of new enantiopure Δ3-4-arylkainoids

Dany Rondeau, Patrice Gill, Monique Chan, Kenneth Curry, William D. Lubell

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2000

Language:

english

File:

PDF, 128 KB

english, 2000

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